SCHEMBL890442

SCHEMBL890442

O=C(O)C(Cc1ccccc1)=C(Cc1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
AKR1B1 P15121 1/20 0.50
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CTBP2 P56545 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 1/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
SRD5A2 P31213 2/20 0.42
MDM2 Q00987 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
EPHX2 P34913 1/20 0.41
SLC6A2 P23975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11298118 0.90 ALDH1A1 (0.50) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL9355165 0.87 AKR1B1 (0.50) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL384894 0.83 CES1 (0.64) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL384895 0.83 CES1 (0.64) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL3881031 0.83 CES1 (0.64) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL6351584 0.82 POLB (0.51) KMT2AMAPTALDH1A1TDP1
SCHEMBL7525941 0.82 CES1 (0.52) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL28605443 0.82 CES1 (0.52) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL304073 0.81 CES1 (0.61) CES1CES2AKR1B1CYP3A4CYP2C9
SCHEMBL304071 0.81 CES1 (0.61) CES1CES2AKR1B1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3151066-B1 ELECTROPHOTOGRAPHIC TONER TOSHIBA TEC KK (JP) 2019-09-11 EP claimed
US-9939747-B2 Developing agent and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2018-04-10 US claimed
EP-2325700-B1 Electrophotographic toner TOSHIBA TEC KK (JP) 2017-08-16 EP claimed
US-20170038698-A1 DEVELOPING AGENT AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2017-02-09 US claimed
US-12011943-B2 Image forming apparatus TOSHIBA TEC KABUSHIKI KAISHA (JP) 2024-06-18 US disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
US-20230018132-A1 REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME RISO TECHNOLOGIES CORPORATION (JP) 2023-01-19 US disclosed
US-20220297458-A1 IMAGE FORMING APPARATUS TOSHIBA TEC KABUSHIKI KAISHA (JP) 2022-09-22 US disclosed
US-20220169919-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2022-06-02 US disclosed
EP-0908501-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 2003-07-09 EP disclosed
US-6494950-B1 FOUR ESSENTIAL COMPONENTS (A) AN ELECTRON-DONATING CHROMATIC ORGANIC COMPOUND, (B) AN ELECTRON-ACCEPTING COMPOUND, (C) A REACTION MEDIUM DETERMINING THE TEMPERATURES AT WHICH THE COLOR REACTIONS OF COMPONENT (A) WITH COMPONENT (B) TAKE THE PILOT INK CO., LTD. (JP) 2002-12-17 US disclosed
EP-0873881-B1 Reversible thermochromic compositions PILOT INK CO LTD (JP) 2001-10-17 EP disclosed
EP-1084860-A2 Thermochromic microencapsulated pigments THE PILOT INK CO., LTD. (JP) 2001-03-21 EP disclosed
US-6048387-A SPECIFIED DIAZARHODAMINE LACTONE DERIVATIVE AS AN ELECTRON-DONATING COLOR-DEVELOPING ORGANIC COMPOUND THE PILOT INK CO., LTD. (JP) 2000-04-11 US disclosed
US-5919404-A MIXTURE OF COLOR DEVELOPING COMPOUND AND ELECTRON ACCEPTORALKOXYPHENOL COMPOUND THE PILOT INK CO., LTD. (JP) 1999-07-06 US disclosed
EP-0908501-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1999-04-14 EP disclosed
EP-0873881-A1 Reversible thermochromic compositions The Pilot Ink CO., Ltd. (JP) 1998-10-28 EP disclosed