Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.51 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | PLAU | P00749 | 4/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PLAT | P00750 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718116 | 0.82 | F2 (0.52) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718457 | 0.82 | PLG (0.55) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718072 | 0.82 | ITGB3 (0.45) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718100 | 0.79 | TPSAB1 (0.66) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8904666 | 0.79 | ITGB3 (0.62) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718459 | 0.78 | ITGB3 (0.57) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8717795 | 0.77 | F2 (0.57) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718615 | 0.77 | TPSAB1 (0.52) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8713275 | 0.76 | ITGB3 (0.51) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL8718226 | 0.76 | SMN1; SMN2 (0.52) | F2PLGPLAUKLKB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |