SCHEMBL8904694

SCHEMBL8904694

Nc1ccc(Oc2ccc(C(=O)c3cccc(Oc4cccc(C(=O)c5ccc(Oc6ccc(N)cc6)cc5)c4)c3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.63
TNKS O95271 1/20 0.63
PARP15 Q460N3 1/20 0.63
PARP14 Q460N5 1/20 0.63
TNKS2 Q9H2K2 1/20 0.63
PARP2 Q9UGN5 1/20 0.63
ALDH1A1 P00352 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MEN1 O00255 1/20 0.61
MITF O75030 1/20 0.61
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
GFER P55789 1/20 0.61
KMT2A Q03164 1/20 0.61
NLRP1 Q9C000 1/20 0.61
NOD2 Q9HC29 1/20 0.61
STS P08842 6/20 0.56
SRD5A2 P31213 1/20 0.54
AKR1C3 P42330 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7802758 1.00 PARP10 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL308153 1.00 PARP10 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL310329 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL8903435 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL29436294 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL8907997 0.95 ALDH1A1 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL28376674 0.94 STS (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL27188052 0.93 PARP10 (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL203590 0.93 PARP10 (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL15294826 0.93 ALDH1A1 (0.71) PARP10TNKSPARP15PARP14TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650463-A Carbon fiber-reinforced polimide resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-22 US disclosed
US-5554765-A HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-10 US disclosed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP disclosed
US-5457154-A Melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1995-10-10 US disclosed
EP-0523240-A1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed