SCHEMBL308153

SCHEMBL308153

Nc1ccc(Oc2cccc(C(=O)c3ccc(Oc4ccc(C(=O)c5cccc(Oc6ccc(N)cc6)c5)cc4)cc3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.63
TNKS O95271 1/20 0.63
PARP15 Q460N3 1/20 0.63
PARP14 Q460N5 1/20 0.63
TNKS2 Q9H2K2 1/20 0.63
PARP2 Q9UGN5 1/20 0.63
ALDH1A1 P00352 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MEN1 O00255 1/20 0.61
MITF O75030 1/20 0.61
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
GFER P55789 1/20 0.61
KMT2A Q03164 1/20 0.61
NLRP1 Q9C000 1/20 0.61
NOD2 Q9HC29 1/20 0.61
STS P08842 6/20 0.56
SRD5A2 P31213 1/20 0.54
AKR1C3 P42330 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8904694 1.00 PARP10 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL7802758 1.00 PARP10 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL310329 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL8903435 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL29436294 0.97 ALDH1A1 (0.66) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL8907997 0.95 ALDH1A1 (0.63) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL28376674 0.94 STS (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL27188052 0.93 PARP10 (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL203590 0.93 PARP10 (0.59) PARP10TNKSPARP15PARP14TNKS2
SCHEMBL15294826 0.93 ALDH1A1 (0.71) PARP10TNKSPARP15PARP14TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-02-12 US claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
JP-2178327-A None JP disclosed
JP-1217064-A None JP disclosed
JP-63243132-A None JP disclosed
JP-63150252-A None JP disclosed
EP-4401112-A1 SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING SEMICONDUCTOR APPARATUS University of Tsukuba (JP) 2024-07-17 EP disclosed
US-20240227373-A1 MULTILAYER BODY OF INORGANIC SUBSTRATE AND TRANSPARENT HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 US disclosed
US-20240227363-A1 LAMINATE OF INORGANIC SUBSTRATE AND HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 US disclosed
EP-0367482-A1 Polyimides and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-09 EP disclosed
EP-0341052-A2 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-08 EP disclosed
EP-0333406-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-20 EP disclosed
JP-H01217064-A POLYPHENYLENE SULFIDE-BASED RESIN COMPOSITION MITSUI TOATSU CHEM INC 1989-08-30 JP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
JP-S63243132-A POLYIMIDE MITSUI TOATSU CHEM INC 1988-10-11 JP disclosed
JP-S63150252-A 4,4'-BIS(3-(4-AMINOPHENOXY)BENZOYL)DIPHENYL ETHER AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1988-06-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom AOC1, INMT, PRMT6 PARP10 898/4885TNKS 1946/4885PARP15 1078/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 PARP10 847/4885TNKS 972/4885PARP15 1201/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 PARP10 835/4885TNKS 1486/4885PARP15 1060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.