Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905011 | 1.00 | REN (0.54) | RENKLK5 | |
| SCHEMBL6044813 | 0.87 | KLK5 (0.47) | RENKLK5 | |
| SCHEMBL8906152 | 0.86 | REN (0.70) | REN | |
| SCHEMBL6043848 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL6042377 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL6043348 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL6042374 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL9029740 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL6042522 | 0.82 | REN (0.49) | RENKLK5 | |
| SCHEMBL8906235 | 0.81 | REN (0.59) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659065-A | CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS | NOVARTIS CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |