Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044566 | 0.87 | REN (0.51) | REN | |
| SCHEMBL8905014 | 0.86 | REN (0.54) | REN | |
| SCHEMBL8905011 | 0.86 | REN (0.54) | REN | |
| SCHEMBL8905121 | 0.86 | REN (0.58) | REN | |
| SCHEMBL8906405 | 0.82 | REN (0.74) | REN | |
| Hydrochloric Acid SCHEMBL9237327 | 0.82 | REN (0.98) | REN | |
| SCHEMBL6043882 | 0.81 | MEN1 (0.52) | REN | |
| SCHEMBL6042847 | 0.81 | MEN1 (0.52) | REN | |
| SCHEMBL8905339 | 0.81 | REN (0.74) | REN | |
| SCHEMBL4046079 | 0.81 | CAPN1 (0.51) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659065-A | CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS | NOVARTIS CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |