Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 15/20 | 0.36 |
| ▸ | F2 | P00734 | 13/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904382 | 0.90 | ST14 (0.41) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8904747 | 0.89 | ST14 (0.39) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8904820 | 0.87 | ST14 (0.38) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8904170 | 0.86 | ITGB3 (0.40) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8904684 | 0.86 | ITGB3 (0.40) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8905684 | 0.86 | F2 (0.37) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8904665 | 0.85 | F2 (0.39) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8905120 | 0.84 | ITGB3 (0.47) | F2DRD2HTR2A | |
| SCHEMBL8715707 | 0.84 | ITGB3 (0.47) | F2DRD2HTR2A | |
| SCHEMBL8905591 | 0.81 | ITGB3 (0.43) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |