Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904689 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL8904332 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL13198831 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL8645778 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL8904699 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL8904696 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL26560361 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL30981172 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL15747803 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL971318 | 0.71 | SMN1; SMN2 (0.70) | SMN1; SMN2CYP2C19NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |