Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904689 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL8905145 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL22589573 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19BCHE | |
| SCHEMBL8717621 | 0.76 | YAP1 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19BCHE | |
| SCHEMBL8717617 | 0.76 | YAP1 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19BCHE | |
| SCHEMBL5724304 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19BCHE | |
| SCHEMBL10639614 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19TDP1 | |
| SCHEMBL7228086 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL15747761 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19TDP1 | |
| SCHEMBL30415448 | 0.74 | MAPT (0.57) | SMN1; SMN2NPC1RAB9ACYP2C19BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |