Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | PLAT | P00750 | 3/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904956 | 0.81 | F2 (0.41) | F10F2PRSS1PLGPLAU | |
| SCHEMBL8903960 | 0.79 | F2 (0.47) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8906154 | 0.79 | ITGB3 (0.47) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8904848 | 0.78 | PLAU (0.48) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8903880 | 0.77 | F2 (0.41) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8905600 | 0.75 | ITGB3 (0.54) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8903869 | 0.75 | ITGB3 (0.54) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8904679 | 0.74 | PLAU (0.50) | F2ITGB3ITGA2BPRSS1PLG | |
| SCHEMBL8903828 | 0.72 | MEN1 (0.48) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8904683 | 0.71 | ITGB3 (0.43) | F10F2ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |