Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 4/20 | 0.42 |
| ▸ | PLAT | P00750 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903453 | 0.85 | NPC1 (0.48) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL8904679 | 0.82 | PLAU (0.50) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8904886 | 0.82 | PLAU (0.49) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8903960 | 0.80 | F2 (0.47) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8904848 | 0.79 | PLAU (0.48) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8905196 | 0.79 | F10 (0.42) | ITGB3ITGA2BPRSS1TMPRSS15PLG | |
| SCHEMBL8903880 | 0.77 | F2 (0.41) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8903869 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8905600 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PLGPLAU | |
| SCHEMBL8903828 | 0.74 | MEN1 (0.48) | ITGB3ITGA2BPRSS1PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |