Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 7/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | AGT | P01019 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8906887 | 0.85 | EDNRA (0.39) | ALOX5EDNRANOD1NOD2HSPA5 | |
| SCHEMBL9096683 | 0.83 | AGT (0.49) | EDNRAAGT | |
| SCHEMBL8907032 | 0.75 | AGTR1 (0.42) | AGT | |
| SCHEMBL8905154 | 0.74 | AGT (0.40) | AGT | |
| SCHEMBL8906462 | 0.71 | AGTR1 (0.38) | AGT | |
| SCHEMBL8906818 | 0.71 | AGTR1 (0.38) | AGT | |
| SCHEMBL8905649 | 0.71 | AGT (0.41) | EDNRAAGT | |
| SCHEMBL8906584 | 0.70 | AGT (0.34) | AGT | |
| SCHEMBL8392162 | 0.69 | AGT (0.40) | AGT | |
| Water SCHEMBL9096451 | 0.68 | EDNRA (0.48) | EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |