Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905158 | 0.89 | AGT (0.42) | AGTAGTR1AGTR2LMNAMAPK1 | |
| SCHEMBL8906546 | 0.84 | LMNA (0.33) | LMNAMAPK1 | |
| SCHEMBL8905649 | 0.82 | AGT (0.41) | AGTAGTR1AGTR2 | |
| SCHEMBL8788760 | 0.81 | AGT (0.56) | AGTAGTR1AGTR2 | |
| SCHEMBL8906471 | 0.78 | AGTR1 (0.43) | AGTAGTR1AGTR2 | |
| SCHEMBL8907844 | 0.78 | AGT (0.40) | AGTAGTR1AGTR2 | |
| SCHEMBL8907032 | 0.77 | AGTR1 (0.42) | AGTAGTR1AGTR2 | |
| SCHEMBL8907061 | 0.76 | AGTR1 (0.38) | AGTAGTR1AGTR2 | |
| SCHEMBL8906462 | 0.75 | AGTR1 (0.38) | AGTAGTR1AGTR2 | |
| SCHEMBL8905197 | 0.74 | ALOX5 (0.39) | AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |