Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427 | 0.91 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| Acetone SCHEMBL5519066 | 0.89 | TET2 (0.35) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL33514 | 0.85 | TBXAS1 (0.36) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL5685778 | 0.84 | CAMK2A (0.35) | TET2TET3TET1GRIK1GRIK2 | |
| Butylamine SCHEMBL10872129 | 0.84 | GRIK1 (0.33) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL2358462 | 0.84 | TBXAS1 (0.38) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL448594 | 0.84 | TBXAS1 (0.38) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL445702 | 0.84 | TBXAS1 (0.38) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL448242 | 0.84 | TBXAS1 (0.38) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL445917 | 0.84 | TBXAS1 (0.38) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082954-A1 | Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082958-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082958-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element | INTS9, PARG, SMCHD1 | TET2 179/4885TET3 297/4885TET1 136/4885 |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | PCBP1, PUF60, PARG | TET2 3307/4885TET3 1818/4885TET1 2394/4885 |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | PELP1, ERCC1, GLRA1 | TET2 1003/4885TET3 587/4885TET1 276/4885 |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | ERCC1, PARG, EPN1 | TET2 636/4885TET3 650/4885TET1 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.