Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905125 | 0.82 | CCKBR (0.59) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8905133 | 0.82 | CCKBR (0.59) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8905144 | 0.81 | CCKBR (0.61) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8905142 | 0.81 | CCKBR (0.61) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8904887 | 0.81 | CCKBR (0.69) | CCKBR | |
| SCHEMBL8904884 | 0.81 | CCKBR (0.69) | CCKBR | |
| SCHEMBL8904790 | 0.81 | CCKBR (0.73) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8904861 | 0.79 | CCKBR (0.56) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8904859 | 0.79 | CCKBR (0.56) | CCKBRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8904898 | 0.79 | CCKBR (0.63) | CCKBRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |