Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905848 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL8903837 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL8905259 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL8904807 | 0.98 | TSHR (0.47) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL355604 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL5385328 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL10869954 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL28570454 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL8905858 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 | |
| SCHEMBL11305185 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRGAACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |