Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905587 | 0.85 | MAPT (0.51) | MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8906803 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL8788819 | 0.81 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL8905418 | 0.81 | AGTR1 (0.48) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8905363 | 0.78 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8907829 | 0.77 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL8907028 | 0.77 | AGTR1 (0.49) | AGTR1AGTR2 | |
| Water SCHEMBL8907807 | 0.77 | AGTR1 (0.48) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL8906988 | 0.77 | AGTR2 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8906678 | 0.76 | AGTR1 (0.49) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |