SCHEMBL8905850

SCHEMBL8905850

O=[C]NC1(O)CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25235984 0.92
SCHEMBL6814157 0.69 CYP2C19 (0.35) ALDH1A1
SCHEMBL528872 0.68 TSHR (0.32)
SCHEMBL4925574 0.68 DPP4 (0.32)
SCHEMBL9713932 0.68 DPP4 (0.32)
SCHEMBL465465 0.67 ALDH1A1 (0.36) ALDH1A1
SCHEMBL25242905 0.65 PDE4A (0.40) ALDH1A1
SCHEMBL28061397 0.65 DPP4 (0.37)
SCHEMBL9713830 0.65
SCHEMBL8629131 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104151312-B Inhibitors of influenza viruses replication 沃泰克斯药物股份有限公司 2016-06-15 CN disclosed
US-5684029-A HYPOTENSIVE AGENTS KARL THOMAE GMBH (DE) 1997-11-04 US disclosed
US-5587393-A ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION DR. KARL THOMAE GMBH (DE) 1996-12-24 US disclosed
US-5385925-A Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them DR. KARL THOMAE GMBH (DE) 1995-01-31 US disclosed