SCHEMBL8905856

SCHEMBL8905856

O=CN(O)C1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 12/20 0.54
ADH1C P00326 9/20 0.52
ADH4 P08319 3/20 0.50
ADH1B P00325 3/20 0.46
FDPS P14324 1/20 0.37
PHGDH O43175 2/20 0.34
ADH7 P40394 1/20 0.34
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27510273 0.75 PIK3CD (0.36) ADH1AADH1CADH4
SCHEMBL10913207 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL39255 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL14855293 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL8745531 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL10012570 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL10013014 0.72 ADH1A (0.94) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL27470063 0.72 HTR2A (0.35)
SCHEMBL7430076 0.71 ADH1A (0.63) ADH1AADH1CADH4ADH1BFDPS
SCHEMBL5122418 0.70 ADH1A (1.00) ADH1AADH1CADH4ADH1BFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176819-B Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2025-02-14 CN disclosed
CN-119176819-A Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2024-12-24 CN disclosed
US-5684029-A HYPOTENSIVE AGENTS KARL THOMAE GMBH (DE) 1997-11-04 US disclosed
US-5587393-A ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION DR. KARL THOMAE GMBH (DE) 1996-12-24 US disclosed
US-5385925-A Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them DR. KARL THOMAE GMBH (DE) 1995-01-31 US disclosed
US-5025028-A Asthma BOEHRINGER MANNHEIM GMBH (DE) 1991-06-18 US disclosed
US-4906666-A Hydroxamic acids and pharmaceutical compositions containing them, and anti-allergic use thereof BOEHRINGER MANNHEIM GMBH (DE) 1990-03-06 US disclosed