Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058898 | 0.77 | USP2 (0.54) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL7244900 | 0.77 | ALDH1A1 (0.57) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL11627436 | 0.77 | USP2 (0.54) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL10192059 | 0.76 | USP2 (0.52) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL15354727 | 0.76 | USP2 (0.52) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL3954978 | 0.74 | USP2 (0.50) | USP2ALDH1A1ANPEPL3MBTL1KDM4E | |
| SCHEMBL4348780 | 0.74 | USP2 (0.50) | USP2ALDH1A1ANPEPL3MBTL1LMNA | |
| SCHEMBL2607193 | 0.74 | USP2 (0.75) | USP2ALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL17393142 | 0.74 | L3MBTL1 (0.45) | USP2ALDH1A1L3MBTL1KDM4EALOX12 | |
| SCHEMBL19059680 | 0.72 | USP2 (0.72) | USP2ALDH1A1L3MBTL1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654445-A | INTERMEDIATES FOR RENIN INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |