Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393504 | 0.95 | AGTR1 (0.65) | PPARGAGTR1 | |
| SCHEMBL8395737 | 0.89 | PPARG (0.75) | PPARGAGTR1 | |
| SCHEMBL8392926 | 0.88 | AGTR1 (0.65) | PPARGAGTR1 | |
| SCHEMBL8944686 | 0.88 | PPARG (0.76) | PPARG | |
| SCHEMBL8395349 | 0.88 | PPARG (0.65) | PPARGAGTR1 | |
| SCHEMBL8392403 | 0.87 | AGTR1 (0.59) | PPARGAGTR1 | |
| SCHEMBL8788446 | 0.87 | PPARG (0.62) | PPARGAGTR1 | |
| SCHEMBL3635454 | 0.87 | AGTR1 (0.68) | PPARGAGTR1 | |
| SCHEMBL8392670 | 0.86 | AGTR1 (0.62) | PPARGAGTR1 | |
| SCHEMBL8392782 | 0.86 | AGTR1 (0.64) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |