SCHEMBL8944686

SCHEMBL8944686

CCCc1nc2cc3ccccc3cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8395737 0.90 PPARG (0.75) PPARG
SCHEMBL8944380 0.88 PPARG (0.59) PPARG
SCHEMBL8905899 0.88 PPARG (0.71) PPARG
SCHEMBL8391730 0.87 AGTR1 (0.61) PPARG
SCHEMBL8391891 0.87 AGTR1 (0.61) PPARG
SCHEMBL8944532 0.87 PPARG (1.00) PPARG
SCHEMBL8392670 0.86 AGTR1 (0.62) PPARG
SCHEMBL8395915 0.86 AGTR1 (0.62) PPARG
SCHEMBL14855485 0.86 PPARG (0.57) PPARG
SCHEMBL9041845 0.86 PPARG (0.66) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 US disclosed