Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375458 | 0.75 | ACP1 (0.64) | GBA1EGFRPDGFRBKDRTP53 | |
| SCHEMBL7328593 | 0.74 | GBA1 (0.63) | GBA1EGFRPDGFRBKDRLMNA | |
| SCHEMBL3109786 | 0.73 | EGFR (0.63) | GBA1EGFRPDGFRBKDRALDH1A1 | |
| SCHEMBL23577847 | 0.73 | EGFR (0.41) | GBA1EGFRPDGFRBKDRMEN1 | |
| SCHEMBL30014051 | 0.73 | EGFR (0.41) | GBA1EGFRPDGFRBKDRMEN1 | |
| SCHEMBL3121624 | 0.72 | EGFR (0.65) | GBA1EGFRPDGFRBKDRALDH1A1 | |
| SCHEMBL3122164 | 0.72 | EGFR (0.51) | GBA1EGFRPDGFRBKDRACP1 | |
| SCHEMBL30960992 | 0.72 | EGFR (0.51) | GBA1EGFRPDGFRBKDRACP1 | |
| SCHEMBL23577459 | 0.71 | KDR (0.42) | GBA1EGFRPDGFRBKDRMEN1 | |
| SCHEMBL30013845 | 0.71 | KDR (0.42) | GBA1EGFRPDGFRBKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |