Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905679 | 0.93 | PPARA (0.47) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL8904567 | 0.93 | PPARA (0.47) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL8906146 | 0.90 | PPARA (0.43) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL8905830 | 0.89 | EP300 (0.37) | PPARAPPARG | |
| SCHEMBL8046083 | 0.86 | SPHK2 (0.46) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL8660244 | 0.86 | SPHK2 (0.46) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL12809420 | 0.75 | PPARA (0.55) | PPARAPPARGHIF1A | |
| SCHEMBL32675259 | 0.75 | PPARA (0.55) | PPARAPPARGHIF1A | |
| SCHEMBL4452302 | 0.75 | PPARA (0.55) | PPARAPPARGHIF1A | |
| SCHEMBL8904822 | 0.74 | TAAR1 (0.34) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683627-A | NONCRACKING | TOKUYAMA CORPORATION (JP) | 1997-11-04 | — | — | US | disclosed |