Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 3/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660244 | 1.00 | SPHK2 (0.46) | SPHK2SPHK1LPLLIPGPPARG | |
| SCHEMBL8905679 | 0.93 | PPARA (0.47) | SPHK2SPHK1LPLLIPGPPARG | |
| SCHEMBL8904567 | 0.93 | PPARA (0.47) | SPHK2SPHK1LPLLIPGPPARG | |
| SCHEMBL8906146 | 0.89 | PPARA (0.43) | SPHK2SPHK1PPARGPPARA | |
| SCHEMBL8905983 | 0.86 | PPARA (0.41) | SPHK2SPHK1PPARGPPARA | |
| SCHEMBL10411867 | 0.83 | THRA (0.49) | SPHK2SPHK1LPLLIPGTHRA | |
| SCHEMBL7871491 | 0.83 | THRA (0.49) | SPHK2SPHK1LPLLIPGTHRA | |
| SCHEMBL27082092 | 0.83 | THRA (0.49) | SPHK2SPHK1LPLLIPGTHRA | |
| SCHEMBL8904822 | 0.82 | TAAR1 (0.34) | SPHK2SPHK1 | |
| SCHEMBL8905830 | 0.79 | EP300 (0.37) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721326-B1 | CONTRACEPTIVE COMPOSITIONS | HAMPTON ROADS MEDICAL COLLEGE (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0721326-A1 | CONTRACEPTIVE COMPOSITIONS | MEDICAL COLLEGE OF HAMPTON ROADS ON BEHALF OF THE CONRAD PROGRAM (US) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995008981-A9 | CONTRACEPTIVE COMPOSITIONS | — | 1995-05-04 | — | — | WO | disclosed |
| WO-1995008981-A1 | CONTRACEPTIVE COMPOSITIONS | THE MEDICAL COLLEGE OF HAMPTON ROADS ON BEHALF OF THE CONRAD PROGRAM (US) | 1995-04-06 | — | — | WO | disclosed |