Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319439 | 1.00 | CYP1A2 (0.45) | CYP1A2RXFP1ALDH1A1MAPTRAB9A | |
| SCHEMBL6319205 | 0.87 | NPY5R (0.49) | — | |
| SCHEMBL8710834 | 0.86 | CYP1A2 (0.44) | CYP1A2ALDH1A1NPC1LMNAKMT2A | |
| SCHEMBL6320830 | 0.86 | CYP1A2 (0.44) | CYP1A2ALDH1A1NPC1LMNAKMT2A | |
| SCHEMBL8715210 | 0.85 | CYP1A2 (0.44) | CYP1A2RAB9ANPC1HPGDHTT | |
| SCHEMBL6316954 | 0.85 | CYP1A2 (0.44) | CYP1A2RAB9ANPC1HPGDHTT | |
| SCHEMBL6316765 | 0.83 | BDKRB2 (0.45) | — | |
| SCHEMBL8715806 | 0.82 | FCER2 (0.52) | — | |
| SCHEMBL6324655 | 0.82 | MME (0.47) | — | |
| SCHEMBL6316217 | 0.81 | GHSR (0.43) | CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |