Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358503 | 0.82 | MAPT (0.48) | MAPTPKMLMNAKMT2AADORA2A | |
| SCHEMBL17327810 | 0.79 | MAT2A (0.40) | MAPTNOS3NOS2MAT2A | |
| SCHEMBL3793924 | 0.78 | NOS3 (0.36) | MAPTNOS3NOS2MAT2A | |
| SCHEMBL2463447 | 0.76 | KMT2A (0.47) | MAPTPKMLMNAKMT2AADORA2A | |
| SCHEMBL1178128 | 0.73 | — | — | |
| Water SCHEMBL11262034 | 0.71 | MAPT (0.55) | MAPTPKMLMNAKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL1644792 | 0.71 | MAPT (0.55) | MAPTPKMLMNAKMT2ANPC1 | |
| SCHEMBL10402501 | 0.70 | — | — | |
| SCHEMBL1934832 | 0.70 | — | — | |
| SCHEMBL24729665 | 0.67 | MAPT (0.50) | MAPTNOS3NOS2PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698685-A | Morpholino-subunit combinatorial library and method | ANTIVIRALS INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5506337-A | Morpholino-subunit combinatorial library and method | ANTIVIRALS INC. (US) | 1996-04-09 | — | — | US | disclosed |