Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CTSC | P53634 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319015 | 0.82 | CTSK (0.45) | CYP2C19RAB9ACTSCCYP3A4CYP2D6 | |
| SCHEMBL7064788 | 0.78 | CYP2C19 (0.50) | CYP2C19RAB9ACTSCADAM17ALDH1A1 | |
| SCHEMBL27562947 | 0.76 | CYP2C19 (0.46) | CYP2C19RAB9ACTSCCYP3A4ADAM17 | |
| SCHEMBL5271776 | 0.72 | CYP3A4 (0.51) | CYP2C19RAB9ACTSCCYP3A4CYP2D6 | |
| SCHEMBL6242631 | 0.72 | CYP3A4 (0.54) | CYP2C19RAB9ACTSCCYP3A4CYP2D6 | |
| SCHEMBL21978209 | 0.71 | OPRD1 (0.45) | RAB9ASLC6A2SLC6A4ALDH1A1HTT | |
| SCHEMBL21978214 | 0.71 | OPRD1 (0.45) | RAB9ASLC6A2SLC6A4ALDH1A1HTT | |
| SCHEMBL16585738 | 0.70 | CYP2C19 (0.64) | CYP2C19RAB9ACTSCADAM17ALDH1A1 | |
| SCHEMBL8188457 | 0.70 | CYP2C19 (0.64) | CYP2C19RAB9ACTSCALDH1A1PKM | |
| SCHEMBL14019361 | 0.70 | CYP2C19 (0.64) | CYP2C19RAB9ACTSCALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211991-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-03-24 | — | — | CN | disclosed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |