Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 5/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654835 | 0.81 | NCF1 (0.42) | PLGPLATLMNANCF1 | |
| SCHEMBL8899930 | 0.81 | NCF1 (0.42) | PLGPLATLMNANCF1 | |
| Trifluoroacetic Acid SCHEMBL1958022 | 0.76 | PLG (0.40) | PLGPLATLMNACYP2D6F11 | |
| Trifluoroacetic Acid SCHEMBL7707560 | 0.76 | ALDH1A1 (0.40) | HRH4HRH3HSD11B1 | |
| SCHEMBL22835510 | 0.74 | PLG (0.50) | PLGPLATLMNACYP2D6F2 | |
| SCHEMBL3847317 | 0.74 | PLG (0.50) | PLGPLATLMNACYP2D6F2 | |
| SCHEMBL2985536 | 0.74 | PLG (0.50) | PLGPLATLMNACYP2D6F2 | |
| Trifluoroacetic Acid SCHEMBL8901689 | 0.73 | PLG (0.42) | PLGPLATLMNACYP2D6F11 | |
| Trifluoroacetic Acid SCHEMBL8916303 | 0.73 | PLG (0.42) | PLGPLATLMNACYP2D6F11 | |
| Trifluoroacetic Acid SCHEMBL3377548 | 0.73 | PLG (0.44) | PLGPLATLMNACYP2D6F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |