Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 3/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152077 | 0.95 | TSHR (0.34) | TSHRMAPTSMN1; SMN2HSD17B10TP53 | |
| SCHEMBL8906296 | 0.77 | ALDH1A1 (0.35) | TSHRMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8887806 | 0.76 | TSHR (0.36) | TSHRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8887804 | 0.74 | — | — | |
| SCHEMBL8886897 | 0.71 | TSHR (0.34) | TSHRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8845990 | 0.65 | ALDH1A1 (0.38) | POLBALDH1A1HPGD | |
| SCHEMBL6810388 | 0.64 | — | — | |
| SCHEMBL6810382 | 0.64 | — | — | |
| SCHEMBL6810383 | 0.62 | — | — | |
| SCHEMBL13424044 | 0.61 | MAPT (0.33) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602250-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-02-11 | — | — | US | disclosed |