Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887806 | 0.95 | TSHR (0.36) | TSHRMAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL7203141 | 0.85 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL8888122 | 0.83 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8152077 | 0.77 | TSHR (0.34) | TSHRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10467409 | 0.77 | MAPT (0.36) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8887804 | 0.72 | — | — | |
| SCHEMBL8906304 | 0.71 | TSHR (0.36) | TSHRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7177783 | 0.71 | — | — | |
| SCHEMBL8906296 | 0.69 | ALDH1A1 (0.35) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8845990 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602250-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-02-11 | — | — | US | disclosed |