Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 6/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898182 | 0.86 | PNP (0.62) | ALDH1A1PNPGDAGRIA1GRIA2 | |
| Phosphoric Acid SCHEMBL27704102 | 0.79 | PNP (0.54) | ALDH1A1PNPGDAGRIA1GRIA2 | |
| SCHEMBL931969 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL5667616 | 0.78 | PNP (0.73) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL932298 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL10921399 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL16513156 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL4624285 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL32689471 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PNPSLC2A1GDAGRIA1 | |
| SCHEMBL22487898 | 0.78 | ALDH1A1 (0.52) | ALDH1A1PNPSLC2A1GDAGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055540-A1 | COMPOUNDS AS RAS INHIBITORS AND USE THEREOF | D.E. SHAW RESEARCH, LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| US-7608600-B2 | Treating hepatitis C virus infections; antivirals have low toxicity to the host; inhibit Flaviviridae polymerase | IDENIX PHARMACEUTICALS, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-7365057-B2 | Treating hepatitis C virus infections; antivirals have low toxicity to the host; inhibit Flaviviridae polymerase | IDENIX PHARMACEUTICALS, INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-7192936-B2 | Use treating hepatitis C infection optionally with other viricides such as interferons or ribavirin; low toxicity to the host; use of cytosine-based nucleotides or nucleosides having a 2'-trifluoromethyl-ribose moiety which forms a 5'-phosphate or hydroxy moiety in vivo | IDENIX PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-5698685-A | Morpholino-subunit combinatorial library and method | ANTIVIRALS INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5506337-A | Morpholino-subunit combinatorial library and method | ANTIVIRALS INC. (US) | 1996-04-09 | — | — | US | disclosed |
| WO-1995031459-A1 | MORPHOLINO-SUBUNIT COMBINATORIAL LIBRARY AND METHOD | ANTIVIRALS INC. (US) | 1995-11-23 | — | — | WO | disclosed |