SCHEMBL4624285

SCHEMBL4624285

O=c1[nH]cnc2nc(O)[nH]c12

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
SLC2A1 P11166 1/20 0.55
PNP P00491 1/20 0.49
GDA Q9Y2T3 1/20 0.44
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DPP4 P27487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthine SCHEMBL29180270 0.85 PNP (0.62) ALDH1A1PNPGDAGRIA1GRIA2
SCHEMBL8906319 0.78 ALDH1A1 (0.59) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL32689471 0.77 ALDH1A1 (0.57) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL5667616 0.77 PNP (0.73) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL931969 0.77 ALDH1A1 (0.57) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL16513156 0.77 ALDH1A1 (0.57) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL932298 0.77 ALDH1A1 (0.57) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL10921399 0.77 ALDH1A1 (0.57) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL9732084 0.77 ALDH1A1 (0.52) ALDH1A1SLC2A1PNPGDAGRIA1
SCHEMBL3757546 0.74 FGFR1 (0.59) ALDH1A1SLC2A1GRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 US disclosed
EP-1921143-A2 Mutants of desoxycytidine kinase having extended enzymatic activity INSTITUT PASTEUR (FR) 2008-05-14 EP disclosed
EP-1383890-B1 MUTANTS OF DESOXYCYTIDINE KINASE HAVING EXTENDED ENZYMATIC ACTIVITY PASTEUR INSTITUT (FR) 2008-05-14 EP disclosed
EP-1383890-A2 MUTANTS OF DESOXYCYTIDINE KINASE HAVING EXTENDED ENZYMATIC ACTIVITY INSTITUT PASTEUR (FR) 2004-01-28 EP disclosed
WO-2002083892-A2 MUTANTS OF DESOXYCYTIDINE KINASE HAVING EXTENDED ENZYMATIC ACTIVITY INSTITUT PASTEUR (FR) 2002-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ALDH1A1 1153/4885SLC2A1 3963/4885PNP 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.