Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115153 | 0.79 | ALDH1A1 (0.58) | MMP8PIN1POLBALDH1A1RECQL | |
| SCHEMBL14476942 | 0.78 | KCNN4 (0.47) | PTPRCMAPTKCNN4CYP2C19HIF1A | |
| SCHEMBL9574965 | 0.78 | CYP2C19 (0.44) | PTPRCMAPTKCNN4CYP2C19HIF1A | |
| SCHEMBL8130212 | 0.76 | CHRM2 (0.45) | MMP8PIN1POLBALDH1A1RECQL | |
| SCHEMBL8105819 | 0.75 | ALDH1A1 (0.45) | MMP8PIN1POLBALDH1A1RECQL | |
| SCHEMBL29016885 | 0.74 | PPID (0.54) | MMP8PPIDPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL4138812 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2THRBMAPTMEN1 | |
| SCHEMBL19663910 | 0.73 | MMP8 (0.46) | MMP8PIN1POLBALDH1A1RECQL | |
| SCHEMBL13865454 | 0.72 | PPID (0.55) | PPIDPOLBALDH1A1SMN1; SMN2KCNN4 | |
| SCHEMBL7441043 | 0.72 | CYP4F2 (0.37) | MMP8ALDH1A1THRBMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |