Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757850 | 0.79 | CTSK (0.60) | CTSKCTSSCYP3A4ATMRAB9A | |
| SCHEMBL8621692 | 0.79 | CTSK (0.60) | CTSKCTSSCYP3A4ATMRAB9A | |
| SCHEMBL6316639 | 0.79 | CTSK (0.41) | CTSKCTSSRAB9ACYP2C19CTSC | |
| SCHEMBL6315991 | 0.79 | ALDH1A1 (0.43) | CYP3A4RAB9ACYP2C19CTSCALDH1A1 | |
| SCHEMBL6315986 | 0.79 | ALDH1A1 (0.43) | CYP3A4RAB9ACYP2C19CTSCALDH1A1 | |
| SCHEMBL10377814 | 0.77 | CTSK (0.55) | CTSKCTSSATMRAB9ACTSL | |
| SCHEMBL10376376 | 0.77 | CTSK (0.55) | CTSKCTSSATMRAB9ACTSL | |
| SCHEMBL11021058 | 0.75 | CTSK (0.61) | CTSKCTSSATMRAB9ACTSL | |
| SCHEMBL6122022 | 0.75 | CTSK (0.46) | CTSKCTSSCYP3A4ATMCTSL | |
| SCHEMBL13932831 | 0.74 | CTSK (0.60) | CTSKCTSSRAB9ACTSLCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |