Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905224 | 0.95 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1TAAR1PARP15 | |
| SCHEMBL2340489 | 0.82 | DRD2 (0.42) | SLC1A3SLC1A2SLC1A1TAAR1PARP15 | |
| SCHEMBL15412571 | 0.81 | DRD2 (0.41) | SLC1A3SLC1A2SLC1A1TAAR1L3MBTL1 | |
| SCHEMBL13610226 | 0.81 | DRD2 (0.41) | SLC1A3SLC1A2SLC1A1TAAR1L3MBTL1 | |
| SCHEMBL15412981 | 0.81 | DRD2 (0.41) | SLC1A3SLC1A2SLC1A1TAAR1L3MBTL1 | |
| SCHEMBL8945514 | 0.81 | TAAR1 (0.36) | SLC1A3SLC1A2SLC1A1TAAR1PARP15 | |
| SCHEMBL20912423 | 0.80 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1HPGDALDH1A1 | |
| SCHEMBL6042877 | 0.80 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1TAAR1PARP15 | |
| SCHEMBL3356356 | 0.80 | DRD2 (0.43) | SLC1A3SLC1A2SLC1A1TAAR1PARP15 | |
| SCHEMBL8904834 | 0.79 | TAAR1 (0.46) | SLC1A3SLC1A2SLC1A1TAAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659065-A | CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS | NOVARTIS CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |