Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906380 | 1.00 | HTR2A (0.43) | HTR2AHTR2CHTR2BCYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6316354 | 0.99 | HTR2A (0.42) | HTR2AHTR2CHTR2BCYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6316352 | 0.99 | HTR2A (0.42) | HTR2AHTR2CHTR2BCYP2D6CYP3A4 | |
| SCHEMBL6602750 | 0.82 | SLC7A11 (0.41) | HTR2AHTR2CHTR2BZAP70SRC | |
| SCHEMBL6602746 | 0.82 | SLC7A11 (0.41) | HTR2AHTR2CHTR2BZAP70SRC | |
| SCHEMBL6602468 | 0.80 | MMP2 (0.48) | ZAP70TACR1SRC | |
| Hydrochloric Acid SCHEMBL6602463 | 0.79 | MMP2 (0.48) | ZAP70TACR1SRC | |
| Hydrochloric Acid SCHEMBL8168445 | 0.79 | MMP2 (0.48) | ZAP70TACR1SRC | |
| SCHEMBL6600672 | 0.78 | ZAP70 (0.46) | ZAP70SRCMC4RMC5R | |
| Hydrochloric Acid SCHEMBL6600093 | 0.77 | ZAP70 (0.46) | ZAP70SRCMC4RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |