SCHEMBL6602468

SCHEMBL6602468

CCOC(=O)c1noc(C(Cc2ccc3ccccc3c2)NC)n1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.48
BMP1 P13497 2/20 0.48
TACR1 P25103 1/20 0.40
SLC26A6 Q9BXS9 7/20 0.39
ZAP70 P43403 3/20 0.39
SRC P12931 2/20 0.39
DHODH Q02127 1/20 0.39
BRAF P15056 1/20 0.38
RIOK2 Q9BVS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6602463 0.99 MMP2 (0.48) MMP2BMP1TACR1SLC26A6ZAP70
Hydrochloric Acid SCHEMBL8168445 0.99 MMP2 (0.48) MMP2BMP1TACR1SLC26A6ZAP70
SCHEMBL6602634 0.88 MMP2 (0.58) MMP2BMP1SLC26A6
SCHEMBL6602750 0.86 SLC7A11 (0.41) ZAP70SRC
SCHEMBL6602746 0.86 SLC7A11 (0.41) ZAP70SRC
SCHEMBL6600399 0.84 MMP2 (0.47) MMP2BMP1TACR1SLC26A6ZAP70
SCHEMBL6605301 0.84 MMP2 (0.43) MMP2BMP1TACR1ZAP70
Hydrochloric Acid SCHEMBL6600392 0.83 MMP2 (0.46) MMP2BMP1TACR1SLC26A6ZAP70
SCHEMBL8906380 0.80 HTR2A (0.43) TACR1ZAP70SRC
SCHEMBL8906383 0.80 HTR2A (0.43) TACR1ZAP70SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805816-B1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK AS (DK) 2004-07-28 EP disclosed
US-6350767-B1 GROWTH HORMONE RELEASE STIMULANT NOVO NORDISK A/S (DK) 2002-02-26 US disclosed
US-6013658-A ANIMAL GROWTH REGULATORS NOVO NORDISK A/S (DK) 2000-01-11 US disclosed
WO-1996022997-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1996-08-01 WO disclosed