Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632161 | 0.92 | MAPT (0.55) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL7338067 | 0.90 | MAPT (0.53) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL15294555 | 0.89 | SMN1; SMN2 (0.53) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL6015473 | 0.89 | MAPT (0.60) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL22533987 | 0.89 | SMN1; SMN2 (0.55) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL4246402 | 0.85 | SMN1; SMN2 (0.54) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL6093891 | 0.85 | SMN1; SMN2 (0.57) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL2845644 | 0.85 | MAPT (0.53) | L3MBTL1KMT2AMEN1ATMMAPT | |
| SCHEMBL7485743 | 0.85 | F10 (0.52) | MAPTSMN1; SMN2MAPK1PKMGAA | |
| SCHEMBL13908151 | 0.85 | KDM4E (0.47) | KMT2AMAPTSMN1; SMN2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112251770-B | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-112251770-A | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-01-22 | — | — | CN | disclosed |
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |