Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906837 | 0.89 | ALDH1A1 (0.44) | PPARGRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL8906960 | 0.82 | PPARG (0.51) | PPARGALDH1A1KDM4EHSD17B10ABCC3 | |
| SCHEMBL8906550 | 0.81 | ALDH1A1 (0.41) | PPARGRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL8789971 | 0.80 | PPARG (0.65) | PPARGRAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8905630 | 0.80 | KDM4E (0.39) | PPARGRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL8905710 | 0.76 | PPARG (0.57) | PPARGALDH1A1KDM4EHSD17B10ABCC3 | |
| SCHEMBL9094539 | 0.75 | PPARG (0.77) | PPARGALDH1A1KDM4EHSD17B10ABCC3 | |
| SCHEMBL8905159 | 0.75 | F2 (0.38) | PPARGALDH1A1KDM4ESLC6A9SMN1; SMN2 | |
| SCHEMBL8906716 | 0.75 | AGTR1 (0.53) | PPARGALDH1A1KDM4EHSD17B10ABCC3 | |
| SCHEMBL8905808 | 0.74 | ALDH1A1 (0.39) | PPARGRAB9AALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |