Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030864 | 0.84 | — | — | |
| SCHEMBL21611743 | 0.78 | ALDH1A1 (0.38) | AKR1B1 | |
| SCHEMBL1564333 | 0.71 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL24869869 | 0.70 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL10608216 | 0.69 | TP53 (0.34) | PIK3CD | |
| SCHEMBL16862254 | 0.69 | PIK3CD (0.30) | PIK3CD | |
| SCHEMBL25211159 | 0.69 | TP53 (0.34) | PIK3CD | |
| SCHEMBL1774348 | 0.69 | TP53 (0.34) | PIK3CD | |
| SCHEMBL6984487 | 0.68 | ALDH1A1 (0.37) | — | |
| SCHEMBL27286122 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763041-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032975-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | CIBA-GEIGY AG (CH) | 1995-12-07 | — | — | WO | disclosed |