SCHEMBL8906992

SCHEMBL8906992

Cc1cccc(N([O])c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.49
NPC1 O15118 4/20 0.49
ALDH1A1 P00352 2/20 0.49
PAX8 Q06710 2/20 0.49
JAK2 O60674 1/20 0.49
HTT P42858 1/20 0.49
ACHE P22303 2/20 0.46
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
KMT2A Q03164 3/20 0.41
RECQL P46063 1/20 0.41
MEN1 O00255 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50370 0.78 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1HTTCYP3A4
SCHEMBL27706354 0.77 ACHE (0.50) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL6870036 0.77 ACHE (0.50) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL883418 0.77 ACHE (0.50) RAB9ANPC1ALDH1A1PAX8JAK2
Benzene SCHEMBL13561466 0.77 ACHE (0.50) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL13720602 0.76 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL10039954 0.76 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL10065551 0.76 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL22812841 0.76 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1PAX8JAK2
SCHEMBL22601053 0.76 ACHE (0.48) RAB9ANPC1ALDH1A1PAX8JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681903-A REACTING POLYMERIC ALIPHATIC ALKANEDIOL WITH STABLE FREE RADICAL NITROXIDE IN PRESENCE OF NITROGEN OXIDE-GENERATING COMPOUND AND OXIDANT, SEPARATING POLYMERIC ALPHA, OMEGA-DIALDEHYDE AND/OR DIACID SHELL OIL COMPANY (US) 1997-10-28 US disclosed
US-5495045-A REACTING ALKOXYALKANOL WITH STABLE FREE RADICAL NITROXIDE IN PRESENCE OF CERIUM SALT, NITRITE COMPOUND, POLAR SOLVENT, OXIDANT AND WATER SHELL OIL COMPANY (US) 1996-02-27 US disclosed
US-5488154-A REACTING ALKOXYALKANE WITH FREE RADICAL NITROXIDE SHELL OIL COMPANY (US) 1996-01-30 US disclosed
US-5391822-A Reacting corresponding branched alkoxyalkanol with stable free radical nitroxide in presence of nitrogen oxide-generating compound, oxidant and solvent, separating SHELL OIL COMPANY (US) 1995-02-21 US disclosed
US-5380930-A Reacting alkoxyalkanol with a nitroxide SHELL OIL COMPANY (US) 1995-01-10 US disclosed
US-5352824-A Oxidation of alkoxyalkanol using stable free radical nitroxide, copper or iron salt and nitrite catalysts in solvent SHELL OIL COMPANY (US) 1994-10-04 US disclosed
US-5336811-A Reacting corresponding aryl methanol with a free radical nitroxide in the presence of a nitrogen oxide generating compound SHELL OIL COMPANY (US) 1994-08-09 US disclosed