Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371961 | 0.85 | TDP1 (0.49) | ALDH1A1TDP1PTPRCS100A4BCHE | |
| SCHEMBL9630885 | 0.83 | C1R (0.43) | ALDH1A1PTPRCS100A4BCHEACHE | |
| SCHEMBL4375599 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1PTPRCS100A4MAOB | |
| SCHEMBL10887956 | 0.79 | HTT (0.45) | ALDH1A1TDP1LMNAMEN1KMT2A | |
| SCHEMBL10449096 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1KMT2AMAPK1 | |
| SCHEMBL7891444 | 0.79 | MASP2 (0.45) | ALDH1A1TDP1MAOBLMNATSHR | |
| SCHEMBL5096848 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL8656692 | 0.77 | HSD17B10 (0.41) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9798917 | 0.76 | TDP1 (0.46) | ALDH1A1TDP1PTPRCS100A4BCHE | |
| SCHEMBL11385468 | 0.75 | POLB (0.46) | ALDH1A1LMNATSHRKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663055-A | Methods for diagnosing human influenza and 4-position modified chromogenic N-acetylneuraminic acid substrated for use therein | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1997-09-02 | — | — | US | claimed |
| EP-0655064-A1 | CHROMOGENIC REAGENTS | THE UNIVERSITY OF LIVERPOOL (GB) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004539-A9 | CHROMOGENIC REAGENTS | — | 1995-02-23 | — | — | WO | disclosed |
| WO-1994004539-A1 | CHROMOGENIC REAGENTS | THE UNIVERSITY OF LIVERPOOL (GB) | 1994-03-03 | — | — | WO | disclosed |
| US-4739076-A | WATER SOLUBLE, FOR PEPTIDES AND PROTEINS | SOUTHWICK PHILIP L (US) | 1988-04-19 | — | — | US | disclosed |