Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426860 | 0.82 | GAA (0.47) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL1193549 | 0.80 | CREBBP (0.59) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL2450511 | 0.80 | CREBBP (0.59) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL7553760 | 0.80 | PNMT (0.56) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL18402760 | 0.80 | GAA (0.46) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL5807102 | 0.80 | GAA (0.46) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL550431 | 0.80 | CREBBP (0.59) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL4371802 | 0.80 | GAA (0.46) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL22955423 | 0.80 | CREBBP (0.59) | GAAMAPTARPNMTCREBBP | |
| SCHEMBL30288510 | 0.80 | CREBBP (0.59) | GAAMAPTARPNMTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498706-A1 | HETEROCYCLIC COMPOUND AS FGFR INHIBITOR | Guangzhou InnoCare Pharma Tech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0642508-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |