Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8906599 | 0.91 | SMN1; SMN2 (0.44) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL8906600 | 0.87 | RAB9A (0.39) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL8907161 | 0.85 | RAB9A (0.40) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL8905360 | 0.85 | AGTR1 (0.40) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL9096666 | 0.75 | AGTR1 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL8906610 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| SCHEMBL9255199 | 0.72 | AGTR1 (0.45) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL8788831 | 0.72 | AGTR1 (0.41) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| Trifluoroacetic Acid SCHEMBL8906608 | 0.72 | AGTR1 (0.40) | ALDH1A1RAB9AKDM4EHPGDGLA | |
| SCHEMBL8906730 | 0.71 | RAB9A (0.38) | ALDH1A1RAB9AKDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |