Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 2/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657723 | 0.91 | P2RX7 (0.42) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL8654379 | 0.90 | P2RX7 (0.39) | SHMT1SHMT2SIGMAR1P2RX7EPHX2 | |
| SCHEMBL8907284 | 0.89 | RECQL (0.41) | SIGMAR1P2RX7KMT2AERCC1ERCC4 | |
| SCHEMBL8905439 | 0.87 | SHMT1 (0.50) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL6475663 | 0.87 | P2RX7 (0.42) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL6475850 | 0.87 | MEN1 (0.40) | SHMT1SHMT2KMT2A | |
| SCHEMBL8907413 | 0.86 | SHMT1 (0.48) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL8907367 | 0.83 | SHMT1 (0.48) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL8906080 | 0.83 | SHMT1 (0.48) | SHMT1SHMT2SIGMAR1P2RX7KMT2A | |
| SCHEMBL8906957 | 0.82 | SHMT1 (0.47) | SHMT1SHMT2SIGMAR1P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |