Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905502 | 0.92 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2TRPV1ALDH1A1LMNA | |
| SCHEMBL6483516 | 0.92 | KMT2A (0.42) | KMT2ASMN1; SMN2ALDH1A1LMNATHRB | |
| SCHEMBL6483627 | 0.92 | KMT2A (0.42) | KMT2ASMN1; SMN2ALDH1A1LMNATHRB | |
| SCHEMBL8907366 | 0.89 | KMT2A (0.46) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1AKR1B1 | |
| SCHEMBL8906757 | 0.88 | KMT2A (0.48) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1AKR1B1 | |
| SCHEMBL8905949 | 0.88 | KMT2A (0.52) | KMT2ASMN1; SMN2SIGMAR1TRPV1ALDH1A1 | |
| SCHEMBL8906958 | 0.87 | KMT2A (0.47) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1AKR1B1 | |
| SCHEMBL8907230 | 0.86 | KMT2A (0.46) | KMT2ASMN1; SMN2SIGMAR1TRPV1ALDH1A1 | |
| SCHEMBL6765259 | 0.83 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1AKR1B1 | |
| SCHEMBL6475343 | 0.83 | KMT2A (0.42) | KMT2ASMN1; SMN2SIGMAR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |