Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907390 | 0.92 | ALDH1A1 (0.53) | KMT2AALDH1A1TRPV1MAPTP2RX7 | |
| SCHEMBL6475343 | 0.90 | KMT2A (0.42) | KMT2ASIGMAR1ALDH1A1GPR132MAPT | |
| SCHEMBL8907213 | 0.88 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8907206 | 0.88 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1ALDH1A1TRPV1 | |
| SCHEMBL8906506 | 0.88 | KMT2A (0.50) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8906049 | 0.86 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1TRPV1 | |
| SCHEMBL8906824 | 0.86 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1TRPV1 | |
| SCHEMBL8907116 | 0.86 | KMT2A (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 | |
| SCHEMBL8906721 | 0.85 | KMT2A (0.48) | KMT2ASIGMAR1AKR1B1ALDH1A1TRPV1 | |
| SCHEMBL6762566 | 0.82 | ALDH1A1 (0.49) | KMT2ASIGMAR1AKR1B1ALDH1A1SHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |