Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335615 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8966804 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18975256 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL135863 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23014949 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL128978 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL23014965 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL130671 | 1.00 | — | — | |
| SCHEMBL130493 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL131692 | 1.00 | HSD17B10 (0.50) | HSD17B10MAPTCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641767-A | CONVERTING A BILE ACID KETONE TO AN ACETYLIDE WITH A STRONG BASE; CATALYZED HYDROGENATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |