SCHEMBL130493

SCHEMBL130493

C#CCCCCCCCCCCCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
MAPT P10636 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
USP2 O75604 3/20 0.46
CYP3A4 P08684 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 5/20 0.39
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
MIF P14174 1/20 0.35
ALOX15 P16050 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335615 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL8966804 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL18975256 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL135863 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL23014949 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL128978 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL23014965 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL130671 1.00
SCHEMBL8907249 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL131692 1.00 HSD17B10 (0.50) HSD17B10MAPTCYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220362151-A1 LIPOSOME FORMULATION ROSI CHARNI AS (NO) 2022-11-17 US disclosed
US-20220249525-A1 Fatty Acid Compounds for Prevention and Treatment of Neurodegenerative Disorders T OMEGA AS (NO) 2022-08-11 US disclosed
EP-3982948-A1 LIPOSOME FORMULATION Rosi Charni AS (NO) 2022-04-20 EP disclosed
EP-3972693-A1 FATTY ACID COMPOUNDS FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS T Omega AS (NO) 2022-03-30 EP disclosed
WO-2020251368-A1 LIPOSOME FORMULATION ROSI CHARNI AS (NO) 2020-12-17 WO disclosed
WO-2020236010-A1 FATTY ACID COMPOUNDS FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS T OMEGA AS (NO) 2020-11-26 WO disclosed
WO-2020236009-A1 FATTY ACID COMPOUNDS FOR PREVENTION AND TREATMENT OF MITOCHONDRIAL DYSFUNCTION T OMEGA AS (NO) 2020-11-26 WO disclosed
EP-3687506-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2020-08-05 EP disclosed
WO-2019195720-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS BIOCRYST PHARMACEUTICALS, INC. (US) 2019-10-10 WO disclosed
US-9029069-B2 Resist underlayer film-forming composition and method for forming pattern JSR CORPORATION (JP) 2015-05-12 US disclosed
EP-1555018-A1 REMEDIES FOR NEURODEGENERATIVE DISEASES Institute of Medicinal Molecular Design, Inc. (JP) 2005-07-20 EP disclosed
EP-1535609-A1 NF-KB ACTIVATION INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-06-01 EP disclosed
EP-1535610-A1 THERAPEUTIC AGENT FOR CANCER Institute of Medicinal Molecular Design, Inc. (JP) 2005-06-01 EP disclosed
EP-1514544-A1 ANTIALLERGIC Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-16 EP disclosed
EP-1512397-A1 O-SUBSTITUTED HYDROXYARYL DERIVATIVES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1512396-A1 INHIBITORS AGAINST THE ACTIVATION OF AP-1 AND NFAT Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-09 EP disclosed
EP-1510207-A1 THERAPEUTIC DRUG FOR DIABETES Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
EP-1510210-A1 IMMUNITY-RELATED PROTEIN KINASE INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2004-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249525-A1 Fatty Acid Compounds for Prevention and Treatment of Neurodegenerative Disorders FABP7, PSEN2, ELOVL1 HSD17B10 259/4885MAPT 25/4885CYP1A2 4065/4885
US-20220362151-A1 LIPOSOME FORMULATION LIPA, NPC1L1, LCAT HSD17B10 438/4885MAPT 2392/4885CYP1A2 1575/4885
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines NFKBIA, IL1B, IKBKB HSD17B10 704/4885MAPT 2435/4885CYP1A2 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.